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AKR7L Knockout cell line (U-2932)

Catalog Number: KOA34596

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Specifications

Product Information
Product Name AKR7L Knockout cell line (U-2932)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Human Lymphocyte-like, suspension
Passage ratio 1:2-1:4
species Human
Gene AKR7L
Gene ID 246181
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line U-2932
Quality Control Genotype: AKR7L Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name aldo-keto reductase family 7 like (gene/pseudogene)provided by HGNC
Also known as AFAR3; AKR7A4; AFB1-AR3; AFB1-AR 3
Gene Description This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Feb 2017]
Expression Biased expression in duodenum (RPKM 22.1), small intestine (RPKM 15.8) and 5 other tissues See more

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