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TBC1D20 Knockout cell line (U-2932)

Catalog Number: KOA36031

Price: Online Inquiry

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Specifications

Product Information
Product Name TBC1D20 Knockout cell line (U-2932)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Human Lymphocyte-like, suspension
Passage ratio 1:2-1:4
species Human
Gene TBC1D20
Gene ID 128637
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line U-2932
Quality Control Genotype: TBC1D20 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name TBC1 domain family member 20provided by HGNC
Also known as WARBM4; C20orf140
Gene Description This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Expression Ubiquitous expression in lung (RPKM 14.1), thyroid (RPKM 13.3) and 25 other tissues See more

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