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SH2B2 Knockout cell line (NCM460)

Catalog Number: KOA73143

Price: Online Inquiry

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Specifications

Product Information
Product Name SH2B2 Knockout cell line (NCM460)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adheren
Passage ratio 1:2~1:3
species Human
Gene SH2B2
Gene ID 10603
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line NCM460
Quality Control Genotype: SH2B2 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name SH2B adaptor protein 2provided by HGNC
Also known as APS
Gene Description The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]
Expression Broad expression in lymph node (RPKM 2.3), spleen (RPKM 2.2) and 22 other tissues See more

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