PNMT Knockout cell line (TPC-1)

Catalog Number: KOA60490

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Specifications

Product Information
Product Name	PNMT Knockout cell line (TPC-1)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:5-1:8
species	Human
Gene	PNMT
Gene ID	5409
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%DMEM+10%FBS
Parental Cell Line	TPC-1
Quality Control	Genotype: PNMT Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	phenylethanolamine N-methyltransferaseprovided by HGNC
Also known as	PENT; PNMTase
Gene Description	The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
Expression	Biased expression in adrenal (RPKM 46.5) and fat (RPKM 2.1) See more

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