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MGLL Knockout cell line (BEAS-2B)

Catalog Number: KOA26479

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Specifications

Product Information
Product Name MGLL Knockout cell line (BEAS-2B)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:3~1:4
species Human
Gene MGLL
Gene ID 11343
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM+10% FBS
Parental Cell Line BEAS-2B
Quality Control Genotype: MGLL Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name monoglyceride lipaseprovided by HGNC
Also known as MGL; HUK5; MAGL; HU-K5
Gene Description This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Expression Broad expression in fat (RPKM 103.8), esophagus (RPKM 51.9) and 19 other tissues See more

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