IGF2R Knockout cell line (BEAS-2B)

Catalog Number: KOA30742

Specifications Downloads Related products

Specifications

Product Information
Product Name	IGF2R Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	IGF2R
Gene ID	3482
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: IGF2R Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	insulin like growth factor 2 receptorprovided by HGNC
Also known as	MPR1; MPRI; CD222; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R
Gene Description	This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
Expression	Ubiquitous expression in spleen (RPKM 12.4), fat (RPKM 11.5) and 25 other tissues See more

Downloads

Datasheet

You may be interested in:

Please note that all services are for research use only. Not intended for any clinical use.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.