HSD3B7 Knockout cell line (BEAS-2B)

Catalog Number: KOA22368

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Specifications

Product Information
Product Name	HSD3B7 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	HSD3B7
Gene ID	80270
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: HSD3B7 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7provided by HGNC
Also known as	CBAS1; PFIC4; SDR11E3
Gene Description	This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Expression	Ubiquitous expression in liver (RPKM 10.0), kidney (RPKM 6.4) and 25 other tissues See more

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