CBFA2T3 Knockout cell line (BEAS-2B)

Catalog Number: KOA32173

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Specifications

Product Information
Product Name	CBFA2T3 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	CBFA2T3
Gene ID	863
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: CBFA2T3 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	CBFA2/RUNX1 partner transcriptional co-repressor 3provided by HGNC
Also known as	ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3
Gene Description	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Expression	Broad expression in spleen (RPKM 6.2), lymph node (RPKM 3.7) and 24 other tissues See more

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