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ACP2 Knockout cell line (TPC-1)

Catalog Number: KOA63458

Price: Online Inquiry

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Specifications

Product Information
Product Name ACP2 Knockout cell line (TPC-1)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:5-1:8
species Human
Gene ACP2
Gene ID 53
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%DMEM+10%FBS
Parental Cell Line TPC-1
Quality Control Genotype: ACP2 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name acid phosphatase 2, lysosomalprovided by HGNC
Also known as LAP
Gene Description The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]
Expression Ubiquitous expression in duodenum (RPKM 19.4), placenta (RPKM 17.1) and 25 other tissues See more

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