Gene: EGR3
Official Full Name: early growth response 3provided by HGNC
Gene Summary: This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38082 | EGR3 Knockout cell line (HCT 116) | Human | EGR3 | 1:2~1:4 | Negative | Online Inquiry |
EGR3 Gene Knockout Cell Lines are advanced biological tools designed for the comprehensive study of the Early Growth Response 3 (EGR3) gene, a crucial transcription factor involved in cellular differentiation and growth processes. These cell lines have undergone targeted gene editing techniques, such as CRISPR/Cas9, to create specific knockouts of the EGR3 gene, allowing researchers to investigate the gene's role in various biological pathways and disease states.
The primary function of EGR3 Gene Knockout Cell Lines is to enable the analysis of EGR3's effects on gene expression, cell signaling, and phenotypic changes within a controlled environment. By studying these knockouts, researchers can elucidate how EGR3 impacts processes such as neurogenesis, immune response, and tumorigenesis. The precise mechanism through which these cell lines operate allows for the development of targeted investigations into EGR3-linked diseases, ultimately facilitating more effective therapeutic strategies.
The scientific importance of these cell lines extends into both research and clinical applications. In research settings, they provide invaluable tools for the investigation of genetic mutations and their implications in health and disease. Clinically, they hold potential for cancer research, studying neurodegenerative diseases, and exploring autoimmune conditions, offering insights that could lead to novel treatment modalities.
What sets EGR3 Gene Knockout Cell Lines apart from conventional cell lines is their specificity and the precision of gene knockout methodologies, ensuring high fidelity in research outcomes. These cell lines are rigorously validated, providing assurance of reproducibility and reliability that is often lacking in alternative models.
For researchers and clinicians alike, the value of EGR3 Gene Knockout Cell Lines lies in their ability to unlock a deeper understanding of gene function and regulatory networks. This enhanced comprehension is essential for developing targeted interventions that could mitigate the impact of related pathologies.
At [Company Name], we pride ourselves in advancing the field of genetic research by providing high-quality, scientifically validated biological products. With our expertise in gene editing technologies and extensive support, we empower researchers to reach their scientific goals with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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