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ST3GAL5 Knockout cell line (AC16)

Catalog Number: KOA12532

Price: Online Inquiry

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Specifications

Product Information
Product Name ST3GAL5 Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene ST3GAL5
Gene ID 8869
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: ST3GAL5 Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 5provided by HGNC
Also known as SATI; SIAT9; SPDRS; ST3GalV; SIATGM3S; ST3Gal V
Gene Description Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression Broad expression in adrenal (RPKM 17.6), thyroid (RPKM 16.1) and 23 other tissues See more

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