SH3BP2 Knockout cell line (U-2932)

Catalog Number: KOA44602

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Specifications

Product Information
Product Name	SH3BP2 Knockout cell line (U-2932)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Human Lymphocyte-like, suspension
Passage ratio	1：2-1：4
species	Human
Gene	SH3BP2
Gene ID	6452
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	U-2932
Quality Control	Genotype: SH3BP2 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	SH3 domain binding protein 2provided by HGNC
Also known as	3BP2; CRBM; CRPM; 3BP-2; RES4-23
Gene Description	The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Expression	Ubiquitous expression in spleen (RPKM 16.5), skin (RPKM 14.5) and 25 other tissues See more

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