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POMK Knockout cell line (BEAS-2B)

Catalog Number: KOA21927

Price: Online Inquiry

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Specifications

Product Information
Product Name POMK Knockout cell line (BEAS-2B)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:3~1:4
species Human
Gene POMK
Gene ID 84197
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM+10% FBS
Parental Cell Line BEAS-2B
Quality Control Genotype: POMK Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name protein O-mannose kinaseprovided by HGNC
Also known as SGK196; MDDGA12; MDDGC12
Gene Description This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Expression Ubiquitous expression in brain (RPKM 2.1), testis (RPKM 1.7) and 25 other tissues See more

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