MMP9 Knockout cell line (BEAS-2B)

Catalog Number: KOA30238

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Specifications

Product Information
Product Name	MMP9 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	MMP9
Gene ID	4318
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: MMP9 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	matrix metallopeptidase 9provided by HGNC
Also known as	GELB; CLG4B; MMP-9; MANDP2
Gene Description	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Expression	Biased expression in bone marrow (RPKM 144.9), lymph node (RPKM 49.8) and 3 other tissues See more

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