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LOX Knockout cell line (AC16)

Catalog Number: KOA14974

Price: Online Inquiry

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Specifications

Product Information
Product Name LOX Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene LOX
Gene ID 4015
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: LOX Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name lysyl oxidaseprovided by HGNC
Also known as AAT10
Gene Description This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
Expression Broad expression in fat (RPKM 18.5), gall bladder (RPKM 11.6) and 21 other tissues See more

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