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IL1A Knockout cell line (AC16)

Catalog Number: KOA15283

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Specifications

Product Information
Product Name IL1A Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene IL1A
Gene ID 3552
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: IL1A Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name interleukin 1 alphaprovided by HGNC
Also known as IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Gene Description The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Expression Biased expression in testis (RPKM 5.2), esophagus (RPKM 4.6) and 7 other tissues See more

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