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CD44 Knockout cell line (AC16)

Catalog Number: KOA16657

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Specifications

Product Information
Product Name CD44 Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene CD44
Gene ID 960
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: CD44 Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name CD44 molecule (IN blood group)provided by HGNC
Also known as IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; H-CAM; HCELL; ECM-III; HUTCH-1; HUTCH-I; ECMR-III; Hermes-1
Gene Description The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Expression Broad expression in skin (RPKM 96.7), appendix (RPKM 60.6) and 19 other tissues See more

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