BTK Knockout cell line (MRC-5)

Catalog Number: KOA93951

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Specifications

Product Information
Product Name	BTK Knockout cell line (MRC-5)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Fibroblast-like, adherent
Passage ratio	1：2-1：3
species	Human
Gene	BTK
Gene ID	695
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%DMEM+10%FBS
Parental Cell Line	MRC-5
Quality Control	Genotype: BTK Knockout cell line (MRC-5)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	Bruton tyrosine kinaseprovided by HGNC
Also known as	AT; ATK; BPK; XLA; IMD1; AGMX1; IGHD3; PSCTK1
Gene Description	The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Expression	Biased expression in lymph node (RPKM 25.2), spleen (RPKM 18.4) and 13 other tissues See more

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