APH1B Knockout cell line (BEAS-2B)

Catalog Number: KOA22127

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Specifications

Product Information
Product Name	APH1B Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	APH1B
Gene ID	83464
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: APH1B Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	aph-1 homolog B, gamma-secretase subunitprovided by HGNC
Also known as	PSFL; APH-1B; PRO1328; TAAV688; aph-1beta
Gene Description	This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
Expression	Broad expression in testis (RPKM 23.1), thyroid (RPKM 13.1) and 22 other tissues See more

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