Gene: ZNF821
Official Full Name: zinc finger protein 821provided by HGNC
Gene Summary: This gene encodes a protein with two C2H2 zinc finger motifs and a score-and-three (23)-amino acid peptide repeat (STPR) domain. The STPR domain of the encoded protein binds to double stranded DNA and may also contain a nuclear localization signal, suggesting that this protein interacts with chromosomal DNA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11955 | ZNF821 Knockout cell line (HeLa) | Human | ZNF821 | 1:3~1:6 | Negative | Online Inquiry |
KO11956 | ZNF821 Knockout cell line (HCT 116) | Human | ZNF821 | 1:2~1:4 | Negative | Online Inquiry |
KO11957 | ZNF821 Knockout cell line (HEK293) | Human | ZNF821 | 1:3~1:6 | Negative | Online Inquiry |
KO11958 | ZNF821 Knockout cell line (A549) | Human | ZNF821 | 1:3~1:4 | Negative | Online Inquiry |
ZNF821 Gene Knockout Cell Lines are advanced biological models designed to facilitate comprehensive functional studies of the ZNF821 gene, a critical transcription factor implicated in various cellular processes, including differentiation, proliferation, and stress responses. By utilizing CRISPR-Cas9 technology, these cell lines feature a precise knockout of the ZNF821 gene, providing researchers with a powerful tool to investigate the gene’s role in cellular mechanisms and disease pathways.
The primary function of ZNF821 Gene Knockout Cell Lines lies in their ability to serve as a comparative baseline for studying the physiological and molecular responses of cells lacking ZNF821. This enables scientists to dissect the gene's contribution to important biological outcomes, such as gene expression regulation and cellular signaling interactions. The knockout approach permits the analysis of phenotypic changes that occur in the absence of ZNF821, thereby enhancing our understanding of its involvement in disease states, including cancer and neurodegenerative disorders.
The scientific importance of these cell lines extends to their utility in both research and clinical settings. They are invaluable for drug discovery and development, allowing researchers to screen therapeutics targeting pathways associated with ZNF821. Additionally, these models can aid in understanding the gene's potential as a biomarker for patient stratification in clinical trials.
What sets ZNF821 Gene Knockout Cell Lines apart from alternative models is their gene-specific and precise editing, which eliminates off-target effects that can confound experimental outcomes. These cell lines are rigorously validated for consistency in performance, ensuring reproducibility critical for robust scientific inquiry.
Researchers and clinicians will find immense value in our ZNF821 Gene Knockout Cell Lines as they pave the way for groundbreaking insights into genetic regulation and disease mechanisms. Our commitment to innovation in biological modeling, backed by a team of experts in genetic engineering and cellular biology, positions us at the forefront of providing high-quality research tools that empower the scientific community to advance their discoveries effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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