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ZNF778 Knockout Cell Lines

Gene: ZNF778

Official Full Name: zinc finger protein 778provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the krueppel C2H2-type zinc-finger protein family, and it contains one KRAB domain and eighteen C2H2-type zinc fingers. This gene is a candidate gene for autism and variable cognitive impairment in the 16q24.3 microdeletion syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21394 ZNF778 Knockout cell line (HeLa) Human ZNF778 1:3~1:6 Negative Online Inquiry
KO21395 ZNF778 Knockout cell line (HCT 116) Human ZNF778 1:2~1:4 Negative Online Inquiry
KO21396 ZNF778 Knockout cell line (HEK293) Human ZNF778 1:3~1:6 Negative Online Inquiry
KO21397 ZNF778 Knockout cell line (A549) Human ZNF778 1:3~1:4 Negative Online Inquiry

Background

ZNF778 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF778 gene, known for its role in transcriptional regulation and cellular immunity, has been specifically disrupted through CRISPR-Cas9 technology. This innovative approach allows researchers to elucidate the function of ZNF778 in various biological processes, including its involvement in cancer biology, cellular differentiation, and immune responses. By creating models devoid of this gene, scientists can study the resultant phenotypic changes and uncover the molecular pathways affected by ZNF778 absence.

The primary function of the ZNF778 gene knockout is to serve as a powerful tool for deciphering gene function through loss-of-function studies. Mechanistically, ZNF778 is implicated in the regulation of gene expression at the transcriptional level, making its knockout particularly relevant for studying gene networks and cell signaling pathways. The engineered cell lines provide a controlled environment for understanding the gene's contribution to diseases, thus facilitating advancements in therapeutic strategies, particularly in oncology and immunology.

From a scientific perspective, these knockout cell lines hold significant importance in both basic and applied research. They enable the validation of gene-targeting therapies and support functional genomics by providing insights into gene behavior in non-diverse cellular contexts. Furthermore, such models are crucial for high-throughput screening applications, allowing researchers to identify potential drug targets or biomarkers associated with ZNF778 signaling.

What sets our ZNF778 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, ensuring that researchers achieve consistent results across experiments. Additionally, these cell lines are validated and optimized for performance in various applications, making them robust tools for both academic and clinical research.

In summary, ZNF778 Gene Knockout Cell Lines offer unique value to researchers and clinicians by providing a reliable platform for functional studies that can expedite discoveries in molecular biology and therapeutic developments. Our company prides itself on its expertise in genetic engineering and cellular models, delivering high-quality biological products that empower the scientific community to push the boundaries of knowledge and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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