Gene: ZNF77
Official Full Name: zinc finger protein 77provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34637 | ZNF77 Knockout cell line (HeLa) | Human | ZNF77 | 1:3~1:6 | Negative | Online Inquiry |
KO34638 | ZNF77 Knockout cell line (HCT 116) | Human | ZNF77 | 1:2~1:4 | Negative | Online Inquiry |
KO34639 | ZNF77 Knockout cell line (HEK293) | Human | ZNF77 | 1:3~1:6 | Negative | Online Inquiry |
KO34640 | ZNF77 Knockout cell line (A549) | Human | ZNF77 | 1:3~1:4 | Negative | Online Inquiry |
ZNF77 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone specific knockout of the ZNFn77 gene, a key regulator in various biological processes, including cell differentiation, proliferation, and apoptosis. By utilizing CRISPR-Cas9 technology or other genome-editing techniques, these cell lines allow researchers to study the functional role of the ZNF77 protein in a controlled environment, facilitating insights into its contribution to cell signaling pathways and disease mechanisms.
The primary function of ZNF77 Gene Knockout Cell Lines lies in their ability to elucidate the consequences of ZNF77 loss-of-function. By observing the phenotypic changes, gene expression alterations, and signaling pathway disruptions upon ZNF77 knockout, researchers can gain valuable insights into its role in oncogenesis and other diseases. This advantage makes these cell lines an essential tool for investigating therapeutic targets and understanding disease biology in both pre-clinical and clinical settings.
The scientific importance of ZNF77 Gene Knockout Cell Lines extends to their wide applications in fundamental research, drug discovery, and personalized medicine. They enable the exploration of gene function in model organisms, thereby advancing our understanding of gene-environment interactions and pathogenesis. In clinical settings, these cell lines can serve as platforms for testing novel therapeutic strategies and assessing drug resistance mechanisms.
Compared to alternative models, ZNF77 Gene Knockout Cell Lines offer several unique advantages, including precise genomic editing, reproducibility, and the ability to generate isogenic control cell lines. This high degree of specificity ensures that the observed phenotypic effects are primarily attributed to the knockout of the ZNF77 gene, reducing background variability common in other experimental models.
For researchers and clinicians, the value of ZNF77 Gene Knockout Cell Lines cannot be overstated. They provide a powerful resource for dissecting gene function and disease processes, ultimately leading to accelerations in research and therapeutic discovery. Our company leverages extensive expertise in genetic engineering and cell biology to offer high-quality ZNF77 Gene Knockout Cell Lines, underscoring our commitment to advancing scientific knowledge and improving clinical outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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