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ZNF746 Knockout Cell Lines

Gene: ZNF746

Official Full Name: zinc finger protein 746provided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in protein complex oligomerization and regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12023 ZNF746 Knockout cell line (HeLa) Human ZNF746 1:3~1:6 Negative Online Inquiry
KO12024 ZNF746 Knockout cell line (HCT 116) Human ZNF746 1:2~1:4 Negative Online Inquiry
KO12025 ZNF746 Knockout cell line (HEK293) Human ZNF746 1:3~1:6 Negative Online Inquiry
KO12026 ZNF746 Knockout cell line (A549) Human ZNF746 1:3~1:4 Negative Online Inquiry

Background

ZNF746 Gene Knockout Cell Lines are specialized cellular models engineered to lack the function of the ZNF746 gene, a critical player in various biological processes including cell cycle regulation and gene expression modulation. These cell lines serve as powerful tools for investigating the functional roles of ZNF746 in both normal physiological contexts and pathological conditions, such as cancer and metabolic disorders.

The key function of ZNF746 involves its zinc-finger protein structure, which allows it to bind to specific DNA sequences and influence transcriptional activity. By employing gene knockout techniques—such as CRISPR-Cas9 or homologous recombination—ZNF746 Gene Knockout Cell Lines exhibit a loss of associated pathways, enabling researchers to dissect the consequences of this gene's absence on cellular behavior, signaling cascades, and phenotypic outcomes.

In the realm of scientific research and clinical applications, these knockout cell lines are invaluable for studying gene function, identifying potential drug targets, and screening for therapeutic interventions that may mitigate the loss of ZNF746 activity. Researchers can leverage these models to further elucidate the molecular underpinnings of diseases linked to dysregulated ZNF746 activity.

One of the standout advantages of using ZNF746 Gene Knockout Cell Lines is the specificity and control they offer compared to other methods of genetic manipulation. Unlike transient knockdowns that can lead to variable expression levels, these stable knockout models provide consistent and reproducible outcomes, thereby enhancing experimental reliability.

For researchers and clinicians focused on gene function and therapeutic discovery, the ZNF746 Gene Knockout Cell Lines present a robust platform to advance our understanding of gene regulation and its implications in human health. Additionally, our company prides itself on its commitment to quality and innovation in biotechnological products, ensuring that researchers have access to the best tools required for cutting-edge scientific inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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