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ZNF717 Knockout Cell Lines

Gene: ZNF717

Official Full Name: zinc finger protein 717provided by HGNC

Gene Summary: This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1. [provided by RefSeq, May 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09763 ZNF717 Knockout cell line (HeLa) Human ZNF717 1:3~1:6 Negative Online Inquiry
KO09764 ZNF717 Knockout cell line (HEK293) Human ZNF717 1:3~1:6 Negative Online Inquiry
KO09765 ZNF717 Knockout cell line (A549) Human ZNF717 1:3~1:4 Negative Online Inquiry

Background

ZNF717 Gene Knockout Cell Lines are specialized cellular models designed for the functional study of the ZNF717 gene, a member of the zinc finger protein family known for its role in transcriptional regulation and cellular processes. Utilizing CRISPR/Cas9 technology, these cell lines facilitate targeted gene knockout, enabling researchers to assess the biological implications of ZNF717 loss-of-function in controlled environments.

The key function of the ZNF717 Gene Knockout Cell Lines revolves around their mechanism of gene silencing, which depletes ZNF717 protein expression, allowing for an in-depth exploration of gene function, interaction networks, and downstream signaling pathways. This is particularly valuable in elucidating the gene's involvement in cancer biology, immune responses, and other pathophysiological conditions. By providing a platform to investigate compensatory mechanisms and phenotypic changes following ZNF717 knockout, these models enhance our understanding of gene functionality in both normal and diseased states.

The scientific importance of these cell lines is underscored by their utility in various research settings, including drug discovery and development, genetic studies, and biomarker identification. Their application extends to unraveling complex diseases, making them indispensable tools for both academic and clinical laboratories.

Compared to other gene knockout systems, ZNF717 Gene Knockout Cell Lines offer several advantages. They are characterized by high specificity, minimal off-target effects, and robustness in experimental reproducibility. Additionally, they are pre-validated for expression and functional assays, saving researchers time and resources typically spent on initial optimization and validation steps.

The value of ZNF717 Gene Knockout Cell Lines lies in their ability to provide critical insights that drive innovative research forward, ultimately contributing to the development of novel therapeutic strategies. With a commitment to advancing scientific discoveries, our company specializes in producing high-quality biological products, ensuring researchers have reliable tools to address complex biological questions.

Please note that all services are for research use only. Not intended for any clinical use.

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