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ZNF652 Knockout Cell Lines

Gene: ZNF652

Official Full Name: zinc finger protein 652provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30289 ZNF652 Knockout cell line (HeLa) Human ZNF652 1:3~1:6 Negative Online Inquiry
KO30290 ZNF652 Knockout cell line (HCT 116) Human ZNF652 1:2~1:4 Negative Online Inquiry
KO30291 ZNF652 Knockout cell line (HEK293) Human ZNF652 1:3~1:6 Negative Online Inquiry
KO30292 ZNF652 Knockout cell line (A549) Human ZNF652 1:3~1:4 Negative Online Inquiry

Background

ZNF652 Gene Knockout Cell Lines are specifically engineered cellular models that have been genetically modified to disrupt the expression of the zinc finger protein 652 (ZNF652). This product serves as a crucial tool for researchers investigating the role of ZNF652 in various biological processes, including cell proliferation, differentiation, and apoptosis, as well as its implications in disease pathogenesis.

The ZNF652 knockout mechanism involves the utilization of CRISPR-Cas9 gene editing technology, which introduces targeted double-strand breaks in the genomic DNA at specific ZNF652 loci. The cellular repair process, relying on non-homologous end joining, leads to frameshift mutations that effectively render the gene inactive, facilitating the study of the resulting phenotypic changes. Researchers can utilize these knockout cell lines to elucidate the gene’s functional role, test therapeutic interventions, or explore gene interaction networks that may underlie complex biological systems.

Scientific importance of ZNF652 Gene Knockout Cell Lines extends beyond basic research. They hold translational potential in clinical settings for understanding roles in oncogenesis and therapeutic resistance in cancers. By facilitating the development of targeted therapies, these cell lines may lead to improved patient outcomes.

Compared to alternative models, ZNF652 Gene Knockout Cell Lines offer the advantage of specificity and homogeneity, as they include not only loss-of-function characteristics but also a controlled genetic background, ensuring reproducibility in experiments. This allows researchers to generate reliable data that can withstand scrutiny in peer review, thus accelerating the pace of scientific discovery.

For researchers, clinicians, and industry professionals, the value of ZNF652 Gene Knockout Cell Lines lies in their ability to significantly advance understanding of gene function, contribute to the identification of novel therapeutic targets, and bridge the gap between laboratory findings and clinical applications. Utilizing these cell lines can streamline projects and enhance the potential for breakthrough discoveries.

With years of expertise in developing robust biological products, our company is committed to delivering high-quality research tools engineered for your success. We stand proud in our mission to empower scientific inquiry and foster innovation through advanced genetic models.

Please note that all services are for research use only. Not intended for any clinical use.

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