Gene: ZNF618
Official Full Name: zinc finger protein 618provided by HGNC
Gene Summary: Enables identical protein binding activity and transcription coregulator binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in pericentric heterochromatin. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30662 | ZNF618 Knockout cell line (HeLa) | Human | ZNF618 | 1:3~1:6 | Negative | Online Inquiry |
KO30663 | ZNF618 Knockout cell line (HCT 116) | Human | ZNF618 | 1:2~1:4 | Negative | Online Inquiry |
KO30664 | ZNF618 Knockout cell line (HEK293) | Human | ZNF618 | 1:3~1:6 | Negative | Online Inquiry |
KO30665 | ZNF618 Knockout cell line (A549) | Human | ZNF618 | 1:3~1:4 | Negative | Online Inquiry |
ZNF618 Gene Knockout Cell Lines are a specialized suite of biological products engineered to enable the precise study of the ZNF618 gene's function and its involvement in various cellular processes. These cell lines are created using advanced CRISPR-Cas9 gene editing technology, which facilitates the targeted disruption of the ZNF618 gene, allowing researchers to investigate the gene's role in gene regulation, protein interaction, and cellular responses to stress or disease.
Functionally, ZNF618 gene knockout cell lines enable the exploration of pathways regulated by the ZNF618 protein, which is implicated in fundamental biological processes such as transcription regulation, DNA repair mechanisms, and cell differentiation. By utilizing these knockout lines, researchers can assess phenotypic changes, evaluate signal transduction pathways, and identify compensatory mechanisms triggered by the loss of ZNF618. This insight is crucial for understanding the gene's ancestral role in oncogenesis and other pathophysiological conditions.
From a scientific perspective, these cell lines hold significant value in both basic research and clinical applications. In particular, they provide a vital tool for elucidating the molecular mechanisms underlying various diseases, including cancer, where ZNF618 has been identified as a potential biomarker or therapeutic target. Moreover, employing knockout models enhances the reproducibility and reliability of experimental outcomes, addressing one of the critical challenges in preclinical research.
Compared to alternative models, ZNF618 gene knockout cell lines offer unique advantages, including specificity of gene disruption and ease of use in high-throughput screening. Their customizable nature allows researchers to select suitable cell backgrounds relevant to their specific experimental needs, ensuring that findings are both contextually relevant and impactful.
For researchers and clinicians looking to uncover the complexities of gene function and regulation, ZNF618 gene knockout cell lines present an unparalleled resource that can lead to breakthroughs in understanding molecular biology and disease mechanisms. Our company specializes in the development of high-quality biological products, underpinned by rigorous validation processes and a commitment to advancing scientific research, ensuring that our offerings support the needs of the global research community effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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