Gene: ZNF543
Official Full Name: zinc finger protein 543provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27500 | ZNF543 Knockout cell line (HeLa) | Human | ZNF543 | 1:3~1:6 | Negative | Online Inquiry |
KO27501 | ZNF543 Knockout cell line (HCT 116) | Human | ZNF543 | 1:2~1:4 | Negative | Online Inquiry |
KO27502 | ZNF543 Knockout cell line (HEK293) | Human | ZNF543 | 1:3~1:6 | Negative | Online Inquiry |
KO27503 | ZNF543 Knockout cell line (A549) | Human | ZNF543 | 1:3~1:4 | Negative | Online Inquiry |
ZNF543 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the functional analysis of the ZNF543 gene, implicated in a range of biological processes, including transcriptional regulation and chromatin modification. These cell lines are generated using advanced CRISPR/Cas9 technology, enabling specific and efficient disruption of the ZNF543 gene, leading to a complete knockout across various cell types. The fundamental mechanism relies on the targeted introduction of double-strand breaks followed by non-homologous end joining, resulting in genetic alterations that help to elucidate the role of ZNF543 in cellular function and disease pathways.
The scientific importance of ZNF543 gene knockout cell lines is underscored by their versatility in both basic research and clinical applications. These cell lines serve as invaluable tools for investigating gene function and regulatory mechanisms, as well as for testing therapeutic interventions targeting the ZNF543-associated pathways. In a clinical setting, they may provide insights into tumor biology, as ZNF543 has been identified in studies involving cancer progression and metastasis.
What sets our ZNF543 Gene Knockout Cell Lines apart from existing alternatives is the precision of our genome-editing techniques and the comprehensive validation processes we implement. Each cell line is rigorously characterized for gene disruption efficiency and phenotypic stability, ensuring that researchers obtain reliable and reproducible data. Furthermore, we provide extensive documentation and support to facilitate easy integration into existing research projects.
For researchers and clinicians, the value of utilizing ZNF543 Gene Knockout Cell Lines lies in the enhanced ability to dissect gene function intricately, coupled with the potential for translational applications. Our expertise in developing high-quality biological products, combined with a commitment to advancing scientific discovery, ensures that users can rely on our cell lines as a robust foundation for their research endeavors. Whether investigating fundamental biological questions or seeking new therapeutic avenues, our ZNF543 Gene Knockout Cell Lines represent a crucial asset in the exploration of gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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