Gene: ZNF525
Official Full Name: zinc finger protein 525provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12185 | ZNF525 Knockout cell line (HeLa) | Human | ZNF525 | 1:3~1:6 | Negative | Online Inquiry |
KO12186 | ZNF525 Knockout cell line (HCT 116) | Human | ZNF525 | 1:2~1:4 | Negative | Online Inquiry |
KO12187 | ZNF525 Knockout cell line (HEK293) | Human | ZNF525 | 1:3~1:6 | Negative | Online Inquiry |
ZNF525 Gene Knockout Cell Lines are specifically engineered cellular models designed to silence the expression of the ZNF525 gene, which encodes a zinc finger protein implicated in various cellular processes, including gene regulation, development, and oncogenesis. These cell lines utilize advanced CRISPR-Cas9 technology to induce targeted double-strand breaks in the genomic DNA, leading to effective gene knockout. This approach enables researchers to create a precise genetic background, thereby facilitating the study of gene function and its biological context.
The primary function of ZNF525 Gene Knockout Cell Lines is to enable the investigation of the ZNF525 gene's role in cellular pathways, signaling mechanisms, and its contribution to disease states, particularly in cancer biology. By comparing the behavior of knockout lines to wild-type controls, researchers can elucidate the gene's role in critical processes such as proliferation, differentiation, and apoptosis. Additionally, these cell lines can serve as invaluable tools for high-throughput screening, drug discovery, and therapeutic development.
The scientific importance of ZNF525 Gene Knockout Cell Lines lies in their application in both fundamental and translational research settings. They provide insights into gene regulatory networks and uncover potential therapeutic targets in diseases where ZNF525 is implicated. Moreover, their use can lead to the identification of novel biomarkers for cancer diagnosis and prognosis.
What sets our ZNF525 Gene Knockout Cell Lines apart is the rigorous validation of the genetic modifications and their functional characterization. This ensures high specificity and reproducibility, crucial for obtaining reliable and interpretable data. Unlike alternative methods that may suffer from off-target effects or unregulated expression of other genes, our targeted approach significantly enhances experimental integrity.
For researchers and clinicians alike, ZNF525 Gene Knockout Cell Lines represent a powerful asset in the quest to unravel gene functions and develop clinically relevant applications. Their ability to simulate disease conditions in vitro provides a critical advantage in both basic research and therapeutic contexts.
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