Gene: ZNF429
Official Full Name: zinc finger protein 429provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12238 | ZNF429 Knockout cell line (HEK293) | Human | ZNF429 | 1:3~1:6 | Negative | Online Inquiry |
ZNF429 Gene Knockout Cell Lines are specialized cell lines that have been genetically modified to eliminate the expression of the ZNF429 gene, an important transcription factor implicated in various cellular processes including proliferation, differentiation, and developmental regulation. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with a robust platform to study the functional consequences of ZNF429 loss, facilitating a deeper understanding of its biological roles and potential implications in diseases such as cancer and genetic disorders.
The primary mechanism of action involves targeted genomic editing, where the ZNF429 gene is precisely disrupted, leading to the production of a knockout phenotype. This allows researchers to observe changes in gene expression, cellular morphology, and biochemical pathways. The loss of ZNF429 can impact gene regulatory networks, making these knockout cell lines invaluable for elucidating the pathways involved in cell signaling and gene regulation.
The scientific significance of ZNF429 Gene Knockout Cell Lines is particularly pronounced in both research and clinical settings. They serve as powerful tools for functional genomics, drug discovery, and therapeutic development, allowing for high-throughput screening of compounds that may target the pathways affected by ZNF429 knockout. Their use extends to cancer research, where understanding the role of transcription factors can lead to innovative treatment strategies.
Compared to other gene knockout models, ZNF429 Gene Knockout Cell Lines offer unparalleled specificity, consistency, and ease of use. With verified genetic modifications, researchers can trust that the phenotypic alterations observed are directly attributable to the knockout. Additionally, these cell lines can be cultured under standard conditions, significantly reducing the time and effort required for experimental setup.
For researchers and clinicians aiming to explore the complex mechanisms of gene function and its potential applications in disease, ZNF429 Gene Knockout Cell Lines represent a critical asset. These products not only enhance the rigor of experimental approaches but also accelerate the progress towards novel therapies.
Our company brings extensive expertise in genetic engineering and cellular biology, ensuring that ZNF429 Gene Knockout Cell Lines are developed with the highest standards of quality and reliability. We are committed to supporting scientific advancement through the provision of superior biological products designed to meet the diverse needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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