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ZNF331 Knockout Cell Lines

Gene: ZNF331

Official Full Name: zinc finger protein 331provided by HGNC

Gene Summary: This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12294 ZNF331 Knockout cell line (HeLa) Human ZNF331 1:3~1:6 Negative Online Inquiry
KO12295 ZNF331 Knockout cell line (HEK293) Human ZNF331 1:3~1:6 Negative Online Inquiry
KO12296 ZNF331 Knockout cell line (A549) Human ZNF331 1:3~1:4 Negative Online Inquiry

Background

ZNF331 Gene Knockout Cell Lines are specially engineered cellular models that facilitate the study of gene function and regulation by eliminating the expression of the ZNF331 gene. This gene encodes a zinc finger protein involved in various biological processes, and its silencing allows researchers to investigate the downstream effects on cellular pathways, gene networks, and phenotypic changes. Utilizing advanced CRISPR-Cas9 technology, these knockout cell lines provide precise genomic modifications while minimizing off-target effects, ensuring reliable and reproducible experimental outcomes.

The key function of the ZNF331 Gene Knockout Cell Lines lies in their ability to shed light on the role of ZNF331 in transcriptional regulation and its implications in diseases such as cancer and developmental disorders. By observing phenotypic variations in cell behavior, differentiation, and signaling pathways, researchers can elucidate the molecular mechanisms at play, paving the way for potential therapeutic targets and biomarkers.

The scientific importance of these knockout cell lines cannot be overstated; they represent critical tools in basic and applied research, bridging the gap between genetic research and clinical applications. Their utility spans across genomics, molecular biology, pharmacology, and disease modeling, making them versatile assets in both academic and biotech laboratories.

Compared to conventional methods, such as siRNA knockdown, ZNF331 Gene Knockout Cell Lines offer a permanent solution for gene disruption, allowing for long-term studies and the exploration of cumulative effects. Additionally, their consistent expression profiles across different experiments enhance data reliability, which is essential for reproducibility in scientific research.

For researchers, clinicians, and pharmaceutical developers aiming to deepen their understanding of gene functions or develop innovative therapeutic strategies, ZNF331 Gene Knockout Cell Lines represent a foundational toolkit that drives discovery and innovation. Our company, specializing in the development of high-quality biological products, ensures that these cell lines are rigorously validated and tailored to meet the specific needs of our customers. With an unwavering commitment to quality and customer satisfaction, we empower scientific advancement through exceptional biological resources.

Please note that all services are for research use only. Not intended for any clinical use.

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