Gene: ZNF283
Official Full Name: zinc finger protein 283provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27932 | ZNF283 Knockout cell line (HeLa) | Human | ZNF283 | 1:3~1:6 | Negative | Online Inquiry |
KO27933 | ZNF283 Knockout cell line (HCT 116) | Human | ZNF283 | 1:2~1:4 | Negative | Online Inquiry |
KO27934 | ZNF283 Knockout cell line (HEK293) | Human | ZNF283 | 1:3~1:6 | Negative | Online Inquiry |
KO27935 | ZNF283 Knockout cell line (A549) | Human | ZNF283 | 1:3~1:4 | Negative | Online Inquiry |
ZNF283 Gene Knockout Cell Lines are genetically engineered models designed to facilitate the study of ZNF283, a transcription factor implicated in various biological processes, including cancer pathology and neurodevelopment. These cell lines are generated using CRISPR-Cas9 technology, allowing for precise gene editing that leads to the complete knockout of the ZNF283 gene. This targeted disruption helps researchers investigate the gene's function in cellular contexts, providing insights into its role in regulatory networks and signal transduction pathways.
The primary function of ZNF283 Gene Knockout Cell Lines lies in their ability to serve as a vital tool for understanding the mechanisms through which ZNF283 influences gene expression and cellular behavior. By studying these knockout lines, scientists can elucidate the gene's involvement in malignant transformation, therapeutic resistance, and other critical phenotypes. Moreover, these cell lines can be utilized in drug screening assays, enabling the identification of therapeutic targets that could mitigate the effects of ZNF283 dysregulation.
In research and clinical settings, ZNF283 Gene Knockout Cell Lines hold significant scientific importance. For instance, they are invaluable in oncology research, where understanding the molecular underpinnings of cancer progression is essential for developing effective treatments. Additionally, they may serve as models for uncovering the genetic components of developmental disorders associated with aberrant transcription factor activity.
Compared to traditional methods of gene knockout, such as homologous recombination, our ZNF283 Gene Knockout Cell Lines offer a more efficient and reproducible approach. The CRISPR-Cas9 method allows for rapid generation and validation of gene disruptions, thereby expediting the research process. Furthermore, our commitment to quality ensures that these cell lines are thoroughly characterized for genetic integrity and functionality, providing researchers with reliable models for their studies.
For researchers, clinicians, and biotech companies looking to deepen their understanding of gene function and its implications in human health, our ZNF283 Gene Knockout Cell Lines present an indispensable resource. They will not only enhance experimental outcomes but also foster innovation in therapeutic development. Our company, with its expertise in providing top-tier biological products, continues to support the advancement of scientific knowledge through a portfolio that prioritizes reliability, accuracy, and user accessibility.
Please note that all services are for research use only. Not intended for any clinical use.
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