Gene: ZNF280A
Official Full Name: zinc finger protein 280Aprovided by HGNC
Gene Summary: This gene encodes a zinc finger protein. The encoded protein contains 4 C2H2-type zinc fingers, which are commonly found in transcription factors. A variety of functions may be performed by this type of zinc finger protein, including the binding of DNA or RNA. [provided by RefSeq, Apr 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26704 | ZNF280A Knockout cell line (HCT 116) | Human | ZNF280A | 1:2~1:4 | Negative | Online Inquiry |
KO26705 | ZNF280A Knockout cell line (A549) | Human | ZNF280A | 1:3~1:4 | Negative | Online Inquiry |
ZNF280A Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to facilitate the study of the ZNF280A gene, which encodes a zinc finger protein implicated in various cellular processes, including transcriptional regulation and DNA repair. By creating knockout cell lines, researchers can effectively silence the expression of the ZNF280A gene, allowing for in-depth investigation of its biological functions and contributions to disease pathways.
These cell lines operate through targeted CRISPR/Cas9 gene-editing technology, which employs a guide RNA to direct the Cas9 nuclease to the specific genomic location of ZNF280A. This mechanism introduces double-strand breaks that lead to gene disruption, resulting in the absence of functional ZNF280A proteins in the resulting cell lines. By utilizing ZNF280A knockout cell lines, researchers can explore how the loss of this gene influences cellular behavior, gene expression profiles, and responses to various stimuli, making them an invaluable resource for functional genomics studies and therapeutic research.
The significance of ZNF280A Gene Knockout Cell Lines extends into both research and clinical applications. They serve as vital platforms for modeling diseases such as cancer, where alterations in gene expression play a crucial role in tumorigenesis and metastasis. Additionally, these cell lines can be employed to test potential pharmacological agents or to refine gene therapies aimed at restoring normal function in disease settings.
Compared to conventional gene silencing methods like RNA interference, our ZNF280A knockout models offer more durable and complete gene disruption, providing a more reliable system for long-term studies. Furthermore, our product is validated for performance in various cell types, enhancing its applicability across different research disciplines.
For researchers and clinicians poised at the forefront of genomic research, ZNF280A Gene Knockout Cell Lines are not just products, but a strategic advantage in the quest to unravel the complexities of gene regulatory networks and their implications in human health. At [Your Company Name], we pride ourselves on our expertise in genetic engineering and our commitment to providing high-quality biological products that empower scientific innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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