Gene: ZNF142
Official Full Name: zinc finger protein 142provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34596 | ZNF142 Knockout cell line (HeLa) | Human | ZNF142 | 1:3~1:6 | Negative | Online Inquiry |
KO34597 | ZNF142 Knockout cell line (HCT 116) | Human | ZNF142 | 1:2~1:4 | Negative | Online Inquiry |
KO34598 | ZNF142 Knockout cell line (HEK293) | Human | ZNF142 | 1:3~1:6 | Negative | Online Inquiry |
KO34599 | ZNF142 Knockout cell line (A549) | Human | ZNF142 | 1:3~1:4 | Negative | Online Inquiry |
ZNF142 Gene Knockout Cell Lines are genetically engineered cellular systems that allow for the targeted disruption of the ZNF142 gene, a gene known to play essential roles in various biological processes, including transcription regulation and cell differentiation. By employing advanced CRISPR-Cas9 technology, these knockout cell lines facilitate the study of the functional consequences of ZNF142 gene loss, thereby providing researchers with valuable insights into gene function and pathophysiology.
The primary mechanism of action of these cell lines involves the introduction of specific guide RNAs that direct the Cas9 nuclease to create double-strand breaks in the ZNF142 gene. The subsequent repair processes often result in insertions or deletions (indels), leading to frameshift mutations that effectively abolish zink finger protein 142 function. This knockout approach enables detailed studies into the gene's role in cellular responses, gene regulation, and disease progression, particularly in cancer research and developmental biology.
The scientific significance of ZNF142 Gene Knockout Cell Lines is profound, as they serve as indispensable tools for elucidating the role of this gene in various contexts, including gene expression studies and drug response assays. Researchers in both academic and clinical laboratories can apply these cell lines to screen for therapeutic targets or understand genetic interactions tied to disease states.
What sets these cellular models apart from alternatives is their high specificity and efficiency in gene editing, which enables more reliable replication of ZNF142 loss-of-function phenotypes. Furthermore, our product is offered with rigorous quality control and validation, ensuring that users can trust the biological relevance and reproducibility of their findings.
For researchers and clinicians aiming to advance their understanding of genetic influences on health and disease, ZNF142 Gene Knockout Cell Lines represent a breakthrough product in the realm of gene editing. Our company prides itself on its expertise in biotechnology and commitment to delivering high-quality biological products that meet the evolving needs of the scientific community, facilitating groundbreaking research and innovative therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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