Gene: ZMYND11
Official Full Name: zinc finger MYND-type containing 11provided by HGNC
Gene Summary: The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31543 | ZMYND11 Knockout cell line (HeLa) | Human | ZMYND11 | 1:3~1:6 | Negative | Online Inquiry |
KO31544 | ZMYND11 Knockout cell line (HCT 116) | Human | ZMYND11 | 1:2~1:4 | Negative | Online Inquiry |
KO31545 | ZMYND11 Knockout cell line (HEK293) | Human | ZMYND11 | 1:3~1:6 | Negative | Online Inquiry |
KO31546 | ZMYND11 Knockout cell line (A549) | Human | ZMYND11 | 1:3~1:4 | Negative | Online Inquiry |
ZMYND11 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the ZMYND11 gene, a critical regulator of various cellular processes, including chromatin remodeling and transcriptional regulation. These knockout cell lines serve as an invaluable tool for researchers investigating the biological functions of ZMYND11, its role in gene expression, and its implications in disease states such as cancer.
The primary mechanism of action involves the disruption of the ZMYND11 gene, which impairs its associated pathways. This enables researchers to study the downstream effects of ZMYND11 absence, providing insights into how its deregulation may lead to altered cellular behaviors, including proliferation, apoptosis, and differentiation. By utilizing these specific cell lines, scientists can conduct focused studies on the gene’s implications in epigenetics, oncology, and developmental biology.
The scientific importance of ZMYND11 Gene Knockout Cell Lines lies in their diverse applications in both basic research and clinical developments. They are instrumental in drug discovery processes, where understanding gene function can lead to the identification of new targets for therapeutic intervention. Moreover, they provide a platform for studying the mechanistic roles of ZMYND11 in various diseases, thus facilitating the development of personalized medicine strategies based on genetic profiling.
In comparison to traditional wild-type cell lines, the ZMYND11 knockout models offer specificity unmatched by alternative approaches, such as RNA interference or CRISPR/Cas9 transient transfections, which may have off-target effects. Additionally, the robustness of these cell lines ensures reproducibility in experimental outcomes, a vital factor in research validity.
For researchers and clinicians invested in advancing the fields of molecular biology and therapeutic development, ZMYND11 Gene Knockout Cell Lines represent a strategic asset. Their availability fosters innovation in understanding the biological ramifications of gene regulation in health and disease.
Our company specializes in high-quality biological products backed by rigorous research and development, ensuring that you receive precise and reliable tools for your scientific endeavors. With a commitment to advancing research through innovation, we prioritize the needs of our end-users, allowing them to achieve their scientific objectives efficiently.
Please note that all services are for research use only. Not intended for any clinical use.
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