Gene: ZFYVE9
Official Full Name: zinc finger FYVE-type containing 9provided by HGNC
Gene Summary: This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11440 | ZFYVE9 Knockout cell line (HeLa) | Human | ZFYVE9 | 1:3~1:6 | Negative | Online Inquiry |
KO11441 | ZFYVE9 Knockout cell line (HCT 116) | Human | ZFYVE9 | 1:2~1:4 | Negative | Online Inquiry |
KO11442 | ZFYVE9 Knockout cell line (HEK293) | Human | ZFYVE9 | 1:3~1:6 | Negative | Online Inquiry |
KO11443 | ZFYVE9 Knockout cell line (A549) | Human | ZFYVE9 | 1:3~1:4 | Negative | Online Inquiry |
ZFYVE9 Gene Knockout Cell Lines are engineered cellular models designed to study the functional consequences of ZFYVE9 gene deletion. This cellular system permits researchers to investigate the biological roles of ZFYVE9 in various physiological and pathological contexts. ZFYVE9, known for its involvement in processes such as cell signaling, cytoskeletal organization, and response to stress, is implicated in numerous diseases, including cancer and neurodegenerative disorders.
The key functionality of ZFYVE9 Gene Knockout Cell Lines lies in their ability to eliminate the expression of the ZFYVE9 protein, thereby providing a clear view of the downstream effects and compensatory mechanisms triggered by the absence of this gene. These knockout models facilitate rigorous experimentation, allowing researchers to observe changes in cell morphology, proliferation, and gene expression profiles as a direct consequence of ZFYVE9 deletion.
In a scientific context, the applications of ZFYVE9 Gene Knockout Cell Lines are multifaceted. They serve as critical tools for elucidating disease mechanisms, validating potential therapeutic targets, and screening compounds for pharmacological intervention. The ability to create precise gene knockouts enhances the reproducibility and reliability of experimental findings, making these cell lines indispensable for both basic research and clinical translational studies.
What sets our ZFYVE9 Gene Knockout Cell Lines apart from alternatives is the meticulous validation of their genetic modification, ensuring that researchers are working with models that accurately reflect the absence of ZFYVE9 expression. This precision not only boosts confidence in experimental outcomes but also enriches the overall utility of the cell lines.
For researchers and clinicians alike, the value of ZFYVE9 Gene Knockout Cell Lines is underscored by their capacity to unlock novel insights into gene function and associated pathways. Our commitment to quality assurance and scientific expertise guarantees that users receive products that meet the highest standards in cellular research.
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