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ZFYVE16 Knockout Cell Lines

Gene: ZFYVE16

Official Full Name: zinc finger FYVE-type containing 16provided by HGNC

Gene Summary: This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11444 ZFYVE16 Knockout cell line (HeLa) Human ZFYVE16 1:3~1:6 Negative Online Inquiry
KO11445 ZFYVE16 Knockout cell line (HCT 116) Human ZFYVE16 1:2~1:4 Negative Online Inquiry
KO11446 ZFYVE16 Knockout cell line (HEK293) Human ZFYVE16 1:3~1:6 Negative Online Inquiry
KO11447 ZFYVE16 Knockout cell line (A549) Human ZFYVE16 1:3~1:4 Negative Online Inquiry

Background

ZFYVE16 Gene Knockout Cell Lines are a groundbreaking biological tool designed to facilitate the study of gene function and regulation. These cell lines are engineered using the CRISPR-Cas9 genome editing technology to disrupt the ZFYVE16 gene, which encodes a protein implicated in various cellular processes, including autophagy and endosomal trafficking. By knocking out this gene, researchers can elucidate the role of ZFYVE16 in cellular pathways and its potential involvement in disease mechanisms.

The primary function of these knockout cell lines is to provide a platform for functional assays that enable scientists to explore the cellular consequences of ZFYVE16 disruption. Through various experimental approaches, such as protein expression analysis, signaling pathway investigations, and phenotypic characterization, researchers can gain a deeper understanding of the gene's contributions to cellular homeostasis and disease states. Furthermore, the knockout model enhances the ability to assess therapeutic targets and develop innovative treatments in both basic and translational research.

The scientific importance of ZFYVE16 Gene Knockout Cell Lines lies not only in basic research but also in clinical applications, particularly in the context of diseases associated with autophagy dysfunction, such as neurodegeneration and cancer. Utilizing these cell lines can lead to significant advancements in understanding the pathology of these conditions and paving the way for the development of targeted therapies.

Compared to alternative methods such as RNA interference or traditional knockout approaches, these cell lines offer a more stable and complete gene disruption, reducing variability and providing more reliable results. Additionally, the ease of use and reproducibility make them advantageous tools for researchers looking for efficiency and precision in their work.

For researchers and clinicians invested in gene function studies and drug discovery, ZFYVE16 Gene Knockout Cell Lines provide an invaluable resource. Their unique properties enable in-depth exploration of genetic and molecular mechanisms in health and disease, promising to drive innovations in biomedical research.

Our company brings years of expertise in cell line development and genetic engineering, and we stand behind our commitment to quality and innovation in providing researchers with cutting-edge biological tools essential for advancing scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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