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ZFPL1 Knockout Cell Lines

Gene: ZFPL1

Official Full Name: zinc finger protein like 1provided by HGNC

Gene Summary: Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34779 ZFPL1 Knockout cell line (HeLa) Human ZFPL1 1:3~1:6 Negative Online Inquiry
KO34780 ZFPL1 Knockout cell line (HCT 116) Human ZFPL1 1:2~1:4 Negative Online Inquiry
KO34781 ZFPL1 Knockout cell line (HEK293) Human ZFPL1 1:3~1:6 Negative Online Inquiry
KO34782 ZFPL1 Knockout cell line (A549) Human ZFPL1 1:3~1:4 Negative Online Inquiry

Background

ZFPL1 Gene Knockout Cell Lines are genetically modified cell lines designed to selectively inactivate the ZFPL1 gene, which encodes a zinc finger protein involved in various cellular processes, including transcriptional regulation and cellular differentiation. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines facilitate the precise and efficient disruption of ZFPL1, allowing researchers to study its functional roles in cellular contexts.

The primary function of ZFPL1 Knockout Cell Lines is to enable the elucidation of the gene's contributions to important biological pathways. By knocking out ZFPL1, researchers can dissect its involvement in gene expression modulation, cell cycle regulation, and response to stressors, providing insights into its role in oncogenesis and other pathologies. The mechanisms by which ZFPL1 influences transcription factors and other downstream signaling pathways can be studied more thoroughly, shedding light on its potential as a therapeutic target in cancer and other diseases.

The scientific importance of these cell lines extends to various research applications, including functional genomics, drug screening, and the study of gene-environment interactions. Additionally, these knockout models are invaluable in translational medicine, where understanding gene function can guide the development of novel therapies. The ability to utilize these specific knockout cell lines in vitro enhances experimental reproducibility and specificity, making findings more reliable.

When compared to traditional methods of gene silencing, such as RNA interference, ZFPL1 Gene Knockout Cell Lines offer a permanent genomic alteration, enabling sustained observation of phenotypic changes over time. This allows researchers to confidently attribute observed effects to the specific loss of ZFPL1 function, rather than transient reductions in gene expression.

ZFPL1 Gene Knockout Cell Lines are essential tools for researchers and clinicians aiming to unravel complex biological mechanisms and identify new therapeutic approaches. Their availability provides a unique opportunity to contribute to cutting-edge research and potential clinical advancements. Our company specializes in the innovative development of biological products designed to facilitate research breakthroughs, and we are committed to supporting the scientific community with high-quality, reliable genetic models.

Please note that all services are for research use only. Not intended for any clinical use.

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