Gene: ZFP69
Official Full Name: ZFP69 zinc finger proteinprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of lipid metabolic process and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12393 | ZFP69 Knockout cell line (HeLa) | Human | ZFP69 | 1:3~1:6 | Negative | Online Inquiry |
KO12394 | ZFP69 Knockout cell line (HEK293) | Human | ZFP69 | 1:3~1:6 | Negative | Online Inquiry |
ZFP69 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to disrupt the ZFP69 gene, which encodes a zinc-finger protein involved in diverse biological processes, including gene regulation and protein interactions. These knockout cell lines serve as valuable tools for probing the gene's functional role in cellular processes and its implications in various diseases.
The primary function of ZFP69 Gene Knockout Cell Lines lies in their ability to facilitate the study of ZFP69-related pathways by eliminating the expression of the gene. This disruption enables researchers to investigate the subsequent phenotypic and molecular changes, providing insights into the gene's contributions to cellular differentiation, proliferation, and apoptosis. By employing techniques such as CRISPR-Cas9 gene editing for knockout generation, these cell lines afford precise genetic modifications, laying the groundwork for detailed mechanistic studies in both developmental biology and disease states.
The scientific importance of ZFP69 Gene Knockout Cell Lines cannot be overstated, particularly in research focusing on developmental disorders, cancer biology, and regenerative medicine. Their application extends to drug discovery and testing, where understanding ZFP69's role could lead to innovative therapeutic strategies targeting specific signaling pathways or cellular responses.
Compared to traditional methods of gene disruption, ZFP69 Gene Knockout Cell Lines present superior advantages, including the reproducibility of knockout efficiency, ease of use, and the ability to generate stable lines that can be propagated over extended periods. Additionally, they provide a more controlled environment for studying the effects of the gene disruption in various biological contexts.
For researchers and clinicians aiming to unravel the complexities of gene function and its clinical implications, these cell lines represent an invaluable asset. The ability to easily assess the biological roles of ZFP69 can drive forward the understanding of related pathologies, leading to breakthroughs in therapeutic development.
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