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ZFP14 Knockout Cell Lines

Gene: ZFP14

Official Full Name: ZFP14 zinc finger proteinprovided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12399 ZFP14 Knockout cell line (HeLa) Human ZFP14 1:3~1:6 Negative Online Inquiry
KO12400 ZFP14 Knockout cell line (HCT 116) Human ZFP14 1:2~1:4 Negative Online Inquiry
KO12401 ZFP14 Knockout cell line (HEK293) Human ZFP14 1:3~1:6 Negative Online Inquiry
KO12402 ZFP14 Knockout cell line (A549) Human ZFP14 1:3~1:4 Negative Online Inquiry

Background

ZFP14 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the zinc finger protein 14 (ZFP14) gene, which plays a critical role in gene regulation and chromatin remodeling. These knockout cell lines serve as essential tools in understanding the functional implications of ZFP14 in various biological processes, including cellular differentiation, proliferation, and response to environmental stimuli.

The primary function of ZFP14 is to act as a transcriptional repressor, modulating gene expression by binding to specific DNA sequences and interacting with coregulators. By utilizing ZFP14 gene knockout cell lines, researchers can investigate the downstream effects of ZFP14 deficiency on gene expression profiles, signaling pathways, and cellular phenotypes. This capability elucidates the gene's roles in both normal physiological conditions and pathological states, thereby enabling deeper insights into diseases where ZFP14 is implicated.

The scientific importance of ZFP14 knockout cell lines is particularly pronounced in research areas focused on developmental biology, cancer, and metabolic disorders. These cell lines enable researchers to develop targeted therapies or gene-editing techniques by providing a clearer understanding of the molecular mechanisms governed by ZFP14.

What sets ZFP14 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability, as they are produced using advanced CRISPR-Cas9 technology, ensuring precise gene disruption without off-target effects. This precision is crucial for generating reproducible results, which is often a challenge with other methods such as RNA interference.

For researchers and clinicians alike, the value of ZFP14 Gene Knockout Cell Lines lies in their ability to facilitate cutting-edge research and accelerate discovery in genetic pathways, drug development, and therapeutic interventions. Their application can lead to the identification of novel biomarkers and potential targets for personalized medicine.

Our company brings over a decade of expertise in the field of genetic engineering and cell line development, offering high-quality products that empower researchers to navigate the complexities of molecular biology effectively. With a commitment to innovation and scientific advancement, we are dedicated to providing cutting-edge tools that support your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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