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ZC3HAV1 Knockout Cell Lines

Gene: ZC3HAV1

Official Full Name: zinc finger CCCH-type containing, antiviral 1provided by HGNC

Gene Summary: This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses, including Ebola virus, HIV and SARS-CoV-2 (which causes COVID-19). [provided by RefSeq, Sep 2021]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04663 ZC3HAV1 Knockout cell line (HeLa) Human ZC3HAV1 1:3~1:6 Negative Online Inquiry
KO04664 ZC3HAV1 Knockout cell line (HCT 116) Human ZC3HAV1 1:2~1:4 Negative Online Inquiry
KO04665 ZC3HAV1 Knockout cell line (HEK293) Human ZC3HAV1 1:3~1:6 Negative Online Inquiry
KO04666 ZC3HAV1 Knockout cell line (A549) Human ZC3HAV1 1:3~1:4 Negative Online Inquiry

Background

ZC3HAV1 Gene Knockout Cell Lines are specialized cell models engineered to disrupt the expression of the ZC3HAV1 gene, which is known to play a crucial role in the modulation of immune responses, particularly in the context of viral infections. These knockout cell lines serve as invaluable tools for researchers seeking to unravel the complex pathways involved in host-pathogen interactions and the regulation of immune mechanisms.

The key function of ZC3HAV1 involves recognizing viral RNA, thereby modulating innate immune signaling pathways such as RIG-I-like Receptor (RLR) and downstream interferon responses. By utilizing ZC3HAV1 knockout cell lines, scientists can investigate how the absence of this gene alters cellular responses to different viral stimuli, enabling a deeper understanding of immune evasion strategies employed by pathogens and potential therapeutic interventions.

In both research and clinical settings, the importance of ZC3HAV1 knockout cell lines cannot be overstated. They allow for the high-throughput screening of antiviral compounds and the exploration of gene function in the context of disease models, particularly those related to viral infections. Furthermore, these cell lines facilitate the study of gene candidate interactions, potentially leading to novel biomarker discoveries and therapeutic targets.

What sets our ZC3HAV1 knockout cell lines apart from other gene knockout models is their rigorous validation for gene deletion and consistent performance across various experimental platforms. These established cell lines reduce unpredictable variables and streamline research workflows, making them an excellent choice for academic and industrial laboratories alike. Additionally, we provide comprehensive support and detailed protocols to ensure optimal use in diverse experimental designs.

For researchers and clinicians aiming to enhance their understanding of viral pathogenesis and the immune response landscape, ZC3HAV1 gene knockout cell lines offer a powerful platform that bridges basic science and applied research. With a commitment to advancing innovative biological products, our company leverages expertise in genomics and cellular biology to support cutting-edge research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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