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ZBTB24 Knockout Cell Lines

Gene: ZBTB24

Official Full Name: zinc finger and BTB domain containing 24provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in nucleus. Implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 2. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32646 ZBTB24 Knockout cell line (HeLa) Human ZBTB24 1:3~1:6 Negative Online Inquiry
KO32647 ZBTB24 Knockout cell line (HCT 116) Human ZBTB24 1:2~1:4 Negative Online Inquiry
KO32648 ZBTB24 Knockout cell line (HEK293) Human ZBTB24 1:3~1:6 Negative Online Inquiry
KO32649 ZBTB24 Knockout cell line (A549) Human ZBTB24 1:3~1:4 Negative Online Inquiry

Background

ZBTB24 Gene Knockout Cell Lines are specialized cellular models engineered to lack the ZBTB24 gene, which encodes a zinc-finger transcription factor implicated in various biological processes, including immune responses and epigenetic regulation. These knockout cell lines serve as vital tools for dissecting the functional role of ZBTB24 in gene expression, cellular signaling pathways, and disease mechanisms, particularly in areas such as cancer research and autoimmune disorders.

The key function of ZBTB24 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function through the absence of ZBTB24. Researchers can utilize these models to understand how the loss of this transcription factor influences cellular behavior, such as proliferation, differentiation, and apoptosis. The mechanisms by which ZBTB24 exerts its effects are multifaceted, involving the interaction with various co-factors and the modulation of chromatin structure, thereby affecting gene transcription levels across numerous cellular contexts.

The scientific importance of ZBTB24 Gene Knockout Cell Lines is evident in their applications for understanding disease pathology, particularly in elucidating the role of ZBTB24 in immune regulation and its potential contribution to tumorigenesis. These models provide a framework for testing therapeutic targets and evaluating drug responses, making them invaluable in both fundamental and translational research settings.

Compared to alternative methods such as knockdown approaches using RNA interference, the gene knockout technique offers a more complete absence of gene function, providing clearer insights into the biological effects of ZBTB24. Furthermore, this product allows for stable expression in various cell types, offering versatility in experimental design.

The value of ZBTB24 Gene Knockout Cell Lines extends to researchers and clinicians who require precise tools for investigating gene functionality and therapeutic interventions. By harnessing the unique characteristics of these cell lines, users can advance their understanding of gene-related mechanisms and contribute to the development of novel therapeutic strategies.

Our company has an established reputation for providing high-quality biological products and expert resources, ensuring that researchers receive reliable and cutting-edge tools to support their scientific endeavors. Join us in advancing biomedicine with ZBTB24 Gene Knockout Cell Lines, where innovation meets reliability in research applications.

Please note that all services are for research use only. Not intended for any clinical use.

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