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XPO6 Knockout Cell Lines

Gene: XPO6

Official Full Name: exportin 6provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29703 XPO6 Knockout cell line (HeLa) Human XPO6 1:3~1:6 Negative Online Inquiry
KO29704 XPO6 Knockout cell line (HCT 116) Human XPO6 1:2~1:4 Negative Online Inquiry
KO29705 XPO6 Knockout cell line (HEK293) Human XPO6 1:3~1:6 Negative Online Inquiry
KO29706 XPO6 Knockout cell line (A549) Human XPO6 1:3~1:4 Negative Online Inquiry

Background

XPO6 Gene Knockout Cell Lines are cutting-edge biological tools designed to facilitate in-depth studies of gene function and regulation by specifically targeting the XPO6 gene, which encodes for a crucial nuclear export protein involved in the transport of RNA and proteins. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of XPO6, allowing researchers to effectively explore the resultant phenotypic changes, cellular pathways, and potential compensatory mechanisms within the cellular environment.

The primary function of XPO6 is to mediate the nuclear export of various substrates, including mRNA and ribosomal proteins. By disrupting the normal function of this export pathway, researchers can examine how alterations in XPO6 impact cellular processes such as gene expression, cellular stress responses, and overall cell viability. This comprehensive understanding is vital for elucidating the roles of XPO6 in disease states, particularly in scenarios of viral infection and cancer, where the manipulation of nuclear transport is often implicated.

Scientifically, XPO6 Gene Knockout Cell Lines have profound implications in research and clinical settings, serving as a model for studying XPO6-related pathologies and therapeutic interventions targeting associated pathways. Furthermore, these cell lines can be integrated into multidisciplinary research efforts, promoting collaborative endeavors across molecular biology, genetics, and drug discovery.

Compared to alternative gene knockout methodologies, our XPO6 Gene Knockout Cell Lines offer unparalleled specificity and efficiency through precise gene editing. This precision minimizes off-target effects, ensuring reliable experimental results that are critical for advancing scientific knowledge. Additionally, our robust validation process guarantees the consistency and reproducibility of these cell lines, which are essential factors in the scientific community.

For researchers and clinicians alike, the value proposition of XPO6 Gene Knockout Cell Lines lies in their ability to yield insightful data that can drive innovation and translate into novel therapeutic strategies. Their application in both fundamental and applied research underscores the necessity of utilizing advanced biological tools for unlocking the complexities of gene function.

At [Your Company Name], we pride ourselves on our expertise in developing high-quality biological products. Our commitment to scientific rigor and innovation positions us as a trusted partner for researchers seeking to enhance their studies with reliable, state-of-the-art solutions like the XPO6 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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