Gene: XPO5
Official Full Name: exportin 5provided by HGNC
Gene Summary: This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00348 | XPO5 gRNA3-gRNA4 KO plasmid | XPO5 | $850 | |||
GP00384 | XPO5 gRNA1-gRNA2 KO plasmid | XPO5 | $850 | |||
KO00713 | XPO5 Knockout cell line(293T) | Human | XPO5 | 1:3~1:6 | Negative | Online Inquiry |
XPO5 Gene Knockout Cell Lines represent a pioneering advancement in the study of nucleocytoplasmic transport and its implications in cellular biology. These cell lines are genetically modified to have a targeted knockout of the XPO5 gene, which encodes a critical exportin involved in the transport of RNA and proteins between the nucleus and cytoplasm. By disrupting the function of XPO5, researchers can elucidate its role in various cellular processes, including gene expression regulation, RNA maturation, and the response to cellular stress.
Functionally, XPO5 mediates the export of specific RNA molecules from the nucleus, making it essential for maintaining proper cellular functions. The knockout of this gene allows researchers to study the resultant phenotypes, providing valuable insights into the mechanisms by which RNA's nuclear-cytoplasmic transport influences various disease states, such as cancer and neurodegenerative disorders. In clinical research, these cell lines can be pivotal in the identification of potential therapeutic targets for modulating RNA transport pathways, opening new avenues for drug development.
The unique advantage of using XPO5 Gene Knockout Cell Lines lies in their specificity and applicability. Unlike traditional cell models, these lines provide a precise tool for investigating the consequences of XPO5 loss, facilitating more reliable experimental outcomes. This specificity is particularly critical in high-throughput screening environments where alternative models may produce ambiguous data.
For researchers and clinicians, the XPO5 Gene Knockout Cell Lines are invaluable resources that enhance the understanding of gene function and the pathology of various diseases. With these tools, researchers can carry out more sophisticated investigations that lead to improved therapeutic strategies and innovations in the field of molecular biology.
Our commitment to advancing scientific research through high-quality biological products is reflected in our expertise and customer support. By choosing XPO5 Gene Knockout Cell Lines, you are equipping yourself with a state-of-the-art resource that is backed by rigorous validation and a thorough understanding of molecular mechanisms, helping to push the boundaries of contemporary biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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