Gene: WSB2
Official Full Name: WD repeat and SOCS box containing 2provided by HGNC
Gene Summary: This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03085 | WSB2 Knockout cell line (HeLa) | Human | WSB2 | 1:3~1:6 | Negative | Online Inquiry |
KO03086 | WSB2 Knockout cell line (HCT 116) | Human | WSB2 | 1:2~1:4 | Negative | Online Inquiry |
KO03087 | WSB2 Knockout cell line (HEK293) | Human | WSB2 | 1:3~1:6 | Negative | Online Inquiry |
KO03088 | WSB2 Knockout cell line (A549) | Human | WSB2 | 1:3~1:4 | Negative | Online Inquiry |
WSB2 Gene Knockout Cell Lines are a specialized set of cellular models that have been genetically engineered to disrupt the expression of the WSB2 gene, a critical regulator involved in various cellular processes, including protein degradation and signal transduction. These cell lines utilize advanced CRISPR/Cas9 gene-editing technology to create knockout variants, enabling researchers to study the specific functions and pathways associated with WSB2 without the influence of its gene product.
The key mechanism of action involves the precise alteration of the WSB2 gene sequence, leading to a non-functional protein that can inhibit its natural biological roles. This disruption facilitates a deeper understanding of the molecular underpinnings of various cellular conditions, such as cancer proliferation, immune response modulation, and developmental biology. By using WSB2 knockout cells, scientists can elucidate the gene's impact on cellular behavior, observe changes in signaling pathways, and assess potential compensatory mechanisms in the absence of WSB2.
The scientific significance of these cell lines extends to both research and clinical applications. In research settings, they provide invaluable models for drug discovery, genetic studies, and investigations into gene functions. Clinically, they hold potential for therapeutic strategies targeting diseases linked to dysregulated WSB2 pathways, particularly in oncology and immunology.
Unlike alternative models that may exhibit residual gene activity or altered expression of compensatory genes, the WSB2 Gene Knockout Cell Lines offer a clean and reliable platform for studying WSB2's role. This specificity enhances the reproducibility and validity of experimental outcomes, making them a preferred choice for researchers seeking definitive insights.
For researchers and clinicians aiming to innovate and excel in their fields, WSB2 Gene Knockout Cell Lines represent an essential tool that enables precise experimentation and the pursuit of novel therapeutic strategies. Our company, renowned for its expertise in genetic modification and cellular technologies, is committed to providing high-quality biological products that empower scientific advancement and improve healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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