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WDR31 Knockout Cell Lines

Gene: WDR31

Official Full Name: WD repeat domain 31provided by HGNC

Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30666 WDR31 Knockout cell line (HCT 116) Human WDR31 1:2~1:4 Negative Online Inquiry
KO30667 WDR31 Knockout cell line (A549) Human WDR31 1:3~1:4 Negative Online Inquiry

Background

WDR31 Gene Knockout Cell Lines are advanced biological research tools specifically designed to study the role of the WDR31 gene in cellular processes. WDR31, or WD Repeat Domain 31, is a gene linked to various crucial cellular functions, including vesicle trafficking and cellular signaling pathways. The knockout of this gene in cell lines allows researchers to create a controlled environment to observe the phenotypic and molecular consequences of its absence, elucidating its function in normal physiology as well as in disease models.

The primary mechanism by which these knockout cell lines operate includes the targeted deletion of the WDR31 gene using CRISPR-Cas9 technology. This precise editing enables a rich investigation of its role in key phenomena such as neurodevelopment and synaptic function. Furthermore, researchers can easily employ these cell lines to perform functional assays, high-throughput screenings, and rescue experiments, contributing significantly to our understanding of genetic and molecular bases of diseases linked with WDR31 dysregulation.

The scientific importance of WDR31 Gene Knockout Cell Lines extends to a range of applications, from basic biological research to the development of therapeutics. These models are particularly valuable in the study of neurodevelopmental disorders, offering insights that can lead to targeted interventions. Furthermore, these cell lines can serve as a platform for drug discovery, allowing researchers to assess potential treatments addressing WDR31-associated pathologies.

What sets WDR31 Gene Knockout Cell Lines apart from similar products is their precise genetic modification achieved through proven CRISPR techniques, ensuring high fidelity in gene editing. Additionally, these cell lines are rigorously characterized, ensuring that researchers are working with reliable and reproducible models, a cornerstone of scientific integrity.

For researchers and clinicians focused on unraveling complex gene-function relationships, investing in WDR31 Gene Knockout Cell Lines is essential. The insights gained can play a pivotal role in advancing scientific knowledge and potentially translating into therapeutic strategies.

At [Your Company Name], we pride ourselves on our extensive expertise in gene editing technologies and our commitment to providing high-quality biological products. Our offerings are tailored to empower researchers in their scientific endeavors, ensuring they have access to cutting-edge tools that facilitate discoveries in genetics and cell biology.

Please note that all services are for research use only. Not intended for any clinical use.

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