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WASHC4 Knockout Cell Lines

Gene: WASHC4

Official Full Name: WASH complex subunit 4provided by HGNC

Gene Summary: This gene encodes a component of the WASH complex, which functions in the intracellular transport of endosomes. Mutations in this gene have been detected in individuals with autosomal recessive cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29456 WASHC4 Knockout cell line (HeLa) Human WASHC4 1:3~1:6 Negative Online Inquiry
KO29457 WASHC4 Knockout cell line (HCT 116) Human WASHC4 1:2~1:4 Negative Online Inquiry
KO29458 WASHC4 Knockout cell line (HEK293) Human WASHC4 1:3~1:6 Negative Online Inquiry
KO29459 WASHC4 Knockout cell line (A549) Human WASHC4 1:3~1:4 Negative Online Inquiry

Background

WASHC4 Gene Knockout Cell Lines are genetically engineered cell models designed to provide researchers with a tool to study the specific functions and regulatory mechanisms of the WASHC4 gene, which plays a crucial role in the modulation of endosomal trafficking and actin dynamics. By generating knockout cell lines, the expression of WASHC4 is completely disabled, allowing for the observation of cellular phenotypes and pathways directly affected by its absence.

The key functions of WASHC4 are tied to its involvement in the Wiskott-Aldrich syndrome protein (WASP)-family protein-mediated endosomal sorting pathways. When WASHC4 is knocked out, researchers have the opportunity to analyze disruptions in intracellular protein transport, which may lead to insights regarding various diseases linked to endosomal dysfunction, such as neurodegenerative disorders or cancers. The knockout cell lines facilitate high-throughput screening, helping elucidate the gene's role in key signaling pathways and providing a basis for future therapeutic targets.

The scientific importance of WASHC4 Gene Knockout Cell Lines extends into both research and clinical settings. These cell lines serve as vital models for investigating the pathophysiological processes influenced by WASHC4, enabling validation of hypotheses in cellular biology, drug development, and genetic studies. They are particularly valuable for personalized medicine approaches, where understanding individual genetic variations can lead to tailored interventions.

What sets our WASHC4 Gene Knockout Cell Lines apart from alternatives is the meticulous design and validation process, ensuring high fidelity in gene disruption and reproducibility in experimental results. Coupled with user-friendly protocols and comprehensive technical support, these cell lines enable seamless integration into existing workflows.

Ultimately, WASHC4 Gene Knockout Cell Lines represent an exceptional resource for researchers and clinicians aiming to deepen their understanding of cellular mechanisms, potentially translating into significant advancements in treatment strategies. Our company prides itself on delivering high-quality biological products backed by extensive expertise in genetic engineering, ensuring our customers have the resources needed to breakthrough in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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