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UBE2Q2 Knockout Cell Lines

Gene: UBE2Q2

Official Full Name: ubiquitin conjugating enzyme E2 Q2provided by HGNC

Gene Summary: Enables ubiquitin-protein transferase activity. Involved in protein K48-linked ubiquitination. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22493 UBE2Q2 Knockout cell line (HeLa) Human UBE2Q2 1:3~1:6 Negative Online Inquiry
KO22494 UBE2Q2 Knockout cell line (HCT 116) Human UBE2Q2 1:2~1:4 Negative Online Inquiry
KO22495 UBE2Q2 Knockout cell line (HEK293) Human UBE2Q2 1:3~1:6 Negative Online Inquiry
KO22496 UBE2Q2 Knockout cell line (A549) Human UBE2Q2 1:3~1:4 Negative Online Inquiry

Background

UBE2Q2 Gene Knockout Cell Lines are genetically modified cellular systems designed specifically to eliminate the expression of the UBE2Q2 gene, which encodes for a ubiquitin-conjugating enzyme involved in protein ubiquitination processes. These knockout cell lines serve as a powerful tool for investigating the functional role of UBE2Q2 in various cellular mechanisms, particularly in the context of protein degradation, cellular signaling pathways, and responses to stressors.

The primary function of the UBE2Q2 Gene Knockout Cell Lines is to facilitate the study of the implications of UBE2Q2 absence in cellular physiology. By removing this crucial gene, researchers can elucidate its involvement in critical processes such as the regulation of the cell cycle, apoptosis, and immune responses. The absence of UBE2Q2 allows for comprehensive investigations into how protein homeostasis is affected, which can have broader implications for understanding diseases, particularly cancer, where ubiquitin-proteasome pathways are frequently dysregulated.

The scientific importance of UBE2Q2 Knockout Cell Lines extends to their application in both basic research and clinical settings. These cell lines enable researchers to decode intricate molecular pathways that involve UBE2Q2, paving the way for biomarker identification and therapeutic target development. Their use can accelerate the discovery of potential interventions in diseases linking to ubiquitin signaling abnormalities.

Compared to other tools in gene editing and functional genomics, the UBE2Q2 Gene Knockout Cell Lines offer significant advantages. Traditional knockout techniques often result in off-target effects or incomplete gene disruption, whereas these specialized cell lines provide a stable and reproducible model with a defined genetic alteration that enhances experimental accuracy. Furthermore, they are ready-to-use, saving time and resources for researchers who can focus directly on experimental outcomes.

By leveraging UBE2Q2 Gene Knockout Cell Lines, researchers and clinicians can deepen their understanding of protein dynamics and pursue novel therapeutic approaches. Our company is dedicated to providing high-quality biological products sustained by expertise in genetic engineering and cell line development. We are committed to empowering scientific discovery with tools that facilitate cutting-edge research and transformative medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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