Gene: TXNDC11
Official Full Name: thioredoxin domain containing 11provided by HGNC
Gene Summary: Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23133 | TXNDC11 Knockout cell line (HeLa) | Human | TXNDC11 | 1:3~1:6 | Negative | Online Inquiry |
KO23134 | TXNDC11 Knockout cell line (HCT 116) | Human | TXNDC11 | 1:2~1:4 | Negative | Online Inquiry |
KO23135 | TXNDC11 Knockout cell line (HEK293) | Human | TXNDC11 | 1:3~1:6 | Negative | Online Inquiry |
KO23136 | TXNDC11 Knockout cell line (A549) | Human | TXNDC11 | 1:3~1:4 | Negative | Online Inquiry |
TXNDC11 Gene Knockout Cell Lines represent a pivotal tool in cellular and molecular biology, specifically designed to facilitate the study of gene function and related biological processes. These cell lines have been genetically modified to inactivate the TXNDC11 gene, which encodes for a protein involved in protein disulfide isomerization and cellular redox homeostasis. By creating knockout models, researchers can effectively investigate the physiological and pathological roles of TXNDC11, including its implications in cancer, neurodegenerative diseases, and metabolic disorders.
The primary function of TXNDC11 Gene Knockout Cell Lines lies in their ability to unravel the intricacies of cellular signaling pathways mediated by oxidative stress and redox balance. Mechanistically, the absence of TXNDC11 allows scientists to discern the downstream effects of disulfide bond formation and protein folding, offering insights into how perturbations in these processes may influence cellular health and disease mechanisms. Utilizing advanced CRISPR-Cas9 technology, these cell lines provide a robust platform for functional genomics research, enabling precise, reproducible experimental designs.
From a scientific perspective, the applications of TXNDC11 Gene Knockout Cell Lines extend into various domains, including drug discovery, biomarker identification, and therapeutic development. Their capacity to model gene function under controlled conditions empowers both researchers and clinicians to explore novel therapeutic avenues, advancing the understanding of target diseases and enhancing treatment strategies.
What sets our TXNDC11 Gene Knockout Cell Lines apart from conventional alternatives is their high specificity and reliability in gene disruption. Unlike traditional RNAi methods that may result in off-target effects, our knockout lines guarantee a thorough and irreversible inactivation of TXNDC11. This unique quality ensures the integrity of experimental data, providing researchers with confidence in their findings.
The value of TXNDC11 Gene Knockout Cell Lines is underscored by their potential to bridge the gap between basic research and clinical applications, making them a crucial asset for any lab focused on gene function studies or disease modeling. With our company’s commitment to innovative biological products and the backing of extensive expertise in gene editing technologies, we deliver these knockout cell lines ready for discovery, ensuring researchers can maximize their investigative potential.
Please note that all services are for research use only. Not intended for any clinical use.
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