Gene: TXN2
Official Full Name: thioredoxin 2provided by HGNC
Gene Summary: This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28754 | TXN2 Knockout cell line (HeLa) | Human | TXN2 | 1:3~1:6 | Negative | Online Inquiry |
KO28755 | TXN2 Knockout cell line (HCT 116) | Human | TXN2 | 1:2~1:4 | Negative | Online Inquiry |
KO28756 | TXN2 Knockout cell line (HEK293) | Human | TXN2 | 1:3~1:6 | Negative | Online Inquiry |
KO28757 | TXN2 Knockout cell line (A549) | Human | TXN2 | 1:3~1:4 | Negative | Online Inquiry |
TXN2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the thioredoxin 2 (TXN2) gene and its associated pathways. These cell lines have been generated through the application of advanced CRISPR-Cas9 gene-editing technology, resulting in stable knockout mutations that enable researchers to investigate the functional role of TXN2 in various biological processes.
The primary function of these knockout cell lines rests in their ability to allow for the examination of TXN2's involvement in redox regulation, mitochondrial function, and cellular stress responses. By eliminating the gene's expression, researchers can better understand the molecular mechanisms by which TXN2 contributes to cellular homeostasis and how its dysregulation may influence diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions.
The scientific importance of TXN2 Gene Knockout Cell Lines is underscored by their utility in basic research, drug development, and therapeutic intervention. These models serve as robust platforms for screening potential pharmaceuticals that target oxidative stress pathways and studying the mechanistic basis of TXN2-related pathological states, providing valuable insights that could lead to novel treatment strategies.
What sets these knockout cell lines apart from traditional models is their unparalleled specificity and reliability, significantly reducing the risk of off-target effects often encountered in other gene-editing methodologies. Additionally, the stable expression of these cell lines can streamline experimental workflows and improve reproducibility across various studies.
For researchers and clinicians focused on oxidative stress and cellular response mechanisms, TXN2 Gene Knockout Cell Lines represent a significant advancement, offering a powerful tool that enriches experimental designs and enhances the depth of data interpretation. These unique models empower users to probe the complexities of gene function and facilitate breakthroughs in understanding disease mechanisms.
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Please note that all services are for research use only. Not intended for any clinical use.
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