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TXK Knockout Cell Lines

Gene: TXK

Official Full Name: TXK tyrosine kinaseprovided by HGNC

Gene Summary: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in positive regulation of macromolecule biosynthetic process; positive regulation of type II interferon-mediated signaling pathway; and protein autophosphorylation. Located in cytosol; nuclear lumen; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34894 TXK Knockout cell line (HCT 116) Human TXK 1:2~1:4 Negative Online Inquiry

Background

TXK Gene Knockout Cell Lines are a powerful tool for researchers aiming to dissect the functional role of the TXK gene within various biological processes. By specifically targeting and disabling the TXK gene, these cell lines allow for the investigation of its contributions to cellular signaling pathways, immune responses, and disease mechanisms. The gene knockout is achieved through CRISPR-Cas9 technology, an advanced genome editing method that provides precision in creating genetic modifications.

The primary function of TXK Gene Knockout Cell Lines is to facilitate loss-of-function studies, enabling scientists to explore the phenotypic consequences of TXK gene disruption. This is particularly crucial for understanding the role of TXK in T cell activation and inflammation, which has implications for various autoimmune diseases and cancers. By analyzing the resultant cellular behaviors, researchers can glean insights into potential therapeutic targets or biomarkers relevant for disease progression.

From a scientific standpoint, these cell lines hold significant importance as they represent an innovative approach towards advancing knowledge in immunology and cellular biology. In clinical settings, this can translate into the development of novel interventions or diagnostic tools based on the understanding gained through these studies.

What sets TXK Gene Knockout Cell Lines apart from alternative models is the precise editing capabilities afforded by CRISPR technology, alongside the robustness of the cell lines that have been optimized for various applications, including high-throughput screening and drug development. Researchers benefit from their reproducibility and high performance, allowing for accelerated research timelines and more reliable data.

For researchers and clinicians, these cell lines offer invaluable contributions towards enhanced understanding and potential treatments of disorders linked to the TXK gene. With our dedication to quality and scientific advancement, our company provides robust and well-characterized biological products, empowering the scientific community to push the boundaries of research and therapeutic discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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